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Mikrobiologie, Virologie und Immunologie

Professor Dr. Selidji Todagbe Agnandji
Fachgebiet: Medizinische Mikrobiologie und Mykologie und Hygiene, Molekulare Infektionsbiologie In Deutschland: 01.10.2024 - 31.12.2024 Projektbeschreibung des Gastgebers Prof. Agnandji is a well-known international expert on vaccine development and malaria. He is a pivotal pillar at CERMEL for the conduct of clinical trials on vaccines against infectious diseases. In the past few years he focused his research on new methods to accelerate the development on vaccines with human challenge models. During his stay in Germany, Prof. Agnandij will continue his research and deepen the collaborations between Lambaréné and Tübingen.	Heimatinstitut Social Science Research Group Centre de Recherches Medicales de Lambarene Campus CERMEL 242 Lambarene Gastinstitut in Deutschland Prof. Dr. Peter G. Kremsner Institut für Tropenmedizin Eberhard Karls Universität Tübingen Wilhelmstraße 27 72074 Tübingen

Professor Dr. Selidji Todagbe Agnandji

Fachgebiet:

Medizinische Mikrobiologie und Mykologie und Hygiene, Molekulare Infektionsbiologie

In Deutschland:

01.10.2024 - 31.12.2024

Projektbeschreibung des Gastgebers

Heimatinstitut

Social Science Research Group
Centre de Recherches Medicales de Lambarene
Campus CERMEL
242 Lambarene

Gastinstitut in Deutschland

Prof. Dr. Peter G. Kremsner
Institut für Tropenmedizin
Eberhard Karls Universität Tübingen
Wilhelmstraße 27
72074 Tübingen

Professor Dr. Raul Andino
Fachgebiet: Virologie In Deutschland: 01.06.2024 - 31.10.2024 Projektbeschreibung des Gastgebers Professor Andino is a leading scientist in the field of RNA virus biology and has made important contributions to our understanding of virus replication and host-pathogen interactions. He combines innovative experimental and computational methods with mathematical modeling to study the evolutionary behavior of RNA viruses and develop novel vaccines. During his research stay in Germany, he will further explore the interaction of the ubiquitin-proteasome system and autophagy in the context of virus defense mechanisms.	Heimatinstitut Department of Microbiology and Immunology University of California, San Francisco 600 16th Street, S572 94143-2280 San Francisco Gastinstitut in Deutschland Prof. Dr. Ivan Dikic Institut für Biochemie II, Universitätsklinikum Gebäude 75 Goethe-Universität Frankfurt am Main Theodor-Stern-Kai 7 60590 Frankfurt am Main

Professor Dr. Raul Andino

Fachgebiet:

Virologie

In Deutschland:

01.06.2024 - 31.10.2024

Projektbeschreibung des Gastgebers

Heimatinstitut

Department of Microbiology and Immunology
University of California, San Francisco
600 16th Street, S572
94143-2280 San Francisco

Gastinstitut in Deutschland

Prof. Dr. Ivan Dikic
Institut für Biochemie II, Universitätsklinikum Gebäude 75
Goethe-Universität Frankfurt am Main
Theodor-Stern-Kai 7
60590 Frankfurt am Main

Professorin Dr. Ludmilla Aristilde
Fachgebiet: Stoffwechselphysiologie, Biochemie und Genetik der Mikroorganismen In Deutschland: 01.01.2022 - 30.06.2022 Projektbeschreibung des Gastgebers Professor Aristilde has a reputation of combining molecular experimental and computational techniques to address fundamental research questions at the interfaces of environmental chemistry, environmental biochemistry and environmental bioengineering. She applies metabolomics approaches for high-resolution chemical fingerprinting of cellular metabolism and has made important contributions in elucidating bacterial carbon recycling. During her stay in Germany, Professor Aristilde intends to uncover new biological ways for sustainable carbon recovery from complex wastes.	Heimatinstitut McCormick School of Engineering & Applied Science Northwestern University 2145 Sheridan Road, Tech A316 60208-3109 Evanston

Professorin Dr. Ludmilla Aristilde

Fachgebiet:

Stoffwechselphysiologie, Biochemie und Genetik der Mikroorganismen

In Deutschland:

01.01.2022 - 30.06.2022

Projektbeschreibung des Gastgebers

Heimatinstitut

McCormick School of Engineering & Applied Science
Northwestern University
2145 Sheridan Road, Tech A316
60208-3109 Evanston

Professor Dr. Belay Tessema Belay
Fachgebiet: Medizinische Mikrobiologie und Mykologie und Hygiene, Molekulare Infektionsbiologie In Deutschland: 01.06.2021 - 31.05.2022 Projektbeschreibung des Gastgebers Professor Belay is an internationally recognized expert in the field of communicable diseases. His scientific focus is tuberculosis, with particular attention to co-infections and antibiotic resistance. His dedicated research on creating novel diagnostics and understanding the epidemiology of these devastating diseases has had significant impacts for improving the diagnosis, management, prevention and control of infectious diseases in Ethiopia. During his stay in Leipzig, he focuses in particular on the interactions between the human immune system and the pathogens.	Heimatinstitut Department of Medical Microbiology University of Gondar 196 Gondar

Professor Dr. Belay Tessema Belay

Fachgebiet:

Medizinische Mikrobiologie und Mykologie und Hygiene, Molekulare Infektionsbiologie

In Deutschland:

01.06.2021 - 31.05.2022

Projektbeschreibung des Gastgebers

Heimatinstitut

Department of Medical Microbiology
University of Gondar
196
Gondar

Professor Dr. Avraham Ben-Nun
Fachgebiet: Immunologie In Deutschland: 01.03.2011 - 31.03.2011 Projektbeschreibung des Gastgebers Dr. Avraham Ben-Nun is one of the leading neuroimmunologists internationally. His contributions have imprinted our concepts of the pathogenesis of multiple sclerosis and of other organ specific autoimmune diseases. Dr. Ben-Nun made his entry into science with a path-breaking discovery. As a young PhD student sharing his time between the Weizmann Institute and the Max-Planck-Institute of Immunobiology Freiburg he was centrally involved in the development of a novel technology, which allowed for the first time the isolation and propagation of autoreactive, autoaggressive T cell lines. This approach then led to the first formal demonstration of autoimmune T cells in the healthy immune repertoire, a discovery, which changed the central concept of immune reactivity and, implicitly, our understanding of autoimmune disease. After a post-doctoral period spent at Harvard Medical School, which introduced him into the then young field of molecular immunology, Dr. Ben-Nun returned to his home institution, the Weizmann Institute, where he built up an independent research group. Avraham Ben-Nun redirected his interest to two main issues, the importance of microbial structures in modulating autoimmune reactions, and the autoimmune response against a particular myelin component, the Myelin Oligodendrocyte Glycoprotein (MOG). He was one of the first to show that, contrary to intuition, microbial products, such as the staphylococcal enterotoxins, heat shock proteins and pertussis toxins may exert beneficial effects on the unfolding myelin-targeted autoimmune response. He furthered that much of this protective activity is exerted by particular regulatory T lymphocytes that oppose the generation of autoaggressive immune cells. Debatably even more visible has been Dr. Ben-Nun's "second leg", his work on immune reactivity against MOG, today one of the most prominent candidate autoantigens in human MS. His group was the first to show that indeed in human MS patients the cellular anti-MOG response is higher than in matched healthy persons. He uses this finding currently to design new and autoantigen specific therapies of human disease. A real blockbuster was his identification of MOG peptide 35-55 as an encephalitogenic autoantigen in the C57BL mouse. This discovery allowed for the first time the predictable induction of EAE in "black" mice, which before were reputed to resist any attempts of autoimmunization. Given that most transgenic mice are being breed on C57BL or on H-2b identical 129/J backgrounds, Ben-Nun's finding opened a completely new avenue to study (CNS) autoimmunity in available transgenic mice. Dr. Ben-Nun will now use his Humboldt Prize to deepen his existent cooperation with the Department of Neuroimmunology (MPI Neurobiology, Martinsried). The two partners plan to use new experimental models of spontaneous myelin autoimmune disease, which had been developed in Martinsried, to validate possible therapeutic effects of Ben-Nun's new immunotherapeutic drugs. The drugs will be tested at different time points before and during spontaneous EAE. There will be particular attention to determinant spreading events that may or may not be affected by the treatments. This cooperation hopefully will help design a new, specific treatment of brain autoimmunity, such as Multiple Sclerosis.	Heimatinstitut Department of Immunology Weizmann Institute of Science PO Box 26, Bldg. Wolfson, Room 330 76100 Rehovot

Professor Dr. Avraham Ben-Nun

Fachgebiet:

Immunologie

In Deutschland:

01.03.2011 - 31.03.2011

Projektbeschreibung des Gastgebers

Dr. Avraham Ben-Nun is one of the leading neuroimmunologists internationally. His contributions have imprinted our concepts of the pathogenesis of multiple sclerosis and of other organ specific autoimmune diseases.

Dr. Ben-Nun made his entry into science with a path-breaking discovery. As a young PhD student sharing his time between the Weizmann Institute and the Max-Planck-Institute of Immunobiology Freiburg he was centrally involved in the development of a novel technology, which allowed for the first time the isolation and propagation of autoreactive, autoaggressive T cell lines. This approach then led to the first formal demonstration of autoimmune T cells in the healthy immune repertoire, a discovery, which changed the central concept of immune reactivity and, implicitly, our understanding of autoimmune disease.

After a post-doctoral period spent at Harvard Medical School, which introduced him into the then young field of molecular immunology, Dr. Ben-Nun returned to his home institution, the Weizmann Institute, where he built up an independent research group.

Avraham Ben-Nun redirected his interest to two main issues, the importance of microbial structures in modulating autoimmune reactions, and the autoimmune response against a particular myelin component, the Myelin Oligodendrocyte Glycoprotein (MOG).

He was one of the first to show that, contrary to intuition, microbial products, such as the staphylococcal enterotoxins, heat shock proteins and pertussis toxins may exert beneficial effects on the unfolding myelin-targeted autoimmune response. He furthered that much of this protective activity is exerted by particular regulatory T lymphocytes that oppose the generation of autoaggressive immune cells.

Debatably even more visible has been Dr. Ben-Nun's "second leg", his work on immune reactivity against MOG, today one of the most prominent candidate autoantigens in human MS. His group was the first to show that indeed in human MS patients the cellular anti-MOG response is higher than in matched healthy persons. He uses this finding currently to design new and autoantigen specific therapies of human disease.

A real blockbuster was his identification of MOG peptide 35-55 as an encephalitogenic autoantigen in the C57BL mouse. This discovery allowed for the first time the predictable induction of EAE in "black" mice, which before were reputed to resist any attempts of autoimmunization. Given that most transgenic mice are being breed on C57BL or on H-2b identical 129/J backgrounds, Ben-Nun's finding opened a completely new avenue to study (CNS) autoimmunity in available transgenic mice.

Dr. Ben-Nun will now use his Humboldt Prize to deepen his existent cooperation with the Department of Neuroimmunology (MPI Neurobiology, Martinsried). The two partners plan to use new experimental models of spontaneous myelin autoimmune disease, which had been developed in Martinsried, to validate possible therapeutic effects of Ben-Nun's new immunotherapeutic drugs. The drugs will be tested at different time points before and during spontaneous EAE. There will be particular attention to determinant spreading events that may or may not be affected by the treatments. This cooperation hopefully will help design a new, specific treatment of brain autoimmunity, such as Multiple Sclerosis.

Heimatinstitut

Department of Immunology
Weizmann Institute of Science
PO Box 26, Bldg. Wolfson, Room 330
76100 Rehovot

Professor Dr. Bruce A. Beutler
Fachgebiet: Immunologie In Deutschland: 01.07.1994 - 31.01.1995	Heimatinstitut Southwestern Medical Center, Center for the Genetics of Host Defense University of Texas at Dallas 5323 Harry Hines Blvd 75390 Dallas

Professor Dr. Bruce A. Beutler

Fachgebiet:

Immunologie

In Deutschland:

01.07.1994 - 31.01.1995

Heimatinstitut

Southwestern Medical Center, Center for the Genetics of Host Defense
University of Texas at Dallas
5323 Harry Hines Blvd
75390 Dallas

Professor Dr. Brendan J. M. Bohannan
Fachgebiet: Mikrobielle Ökologie und Angewandte Mikrobiologie In Deutschland: 01.03.2022 - 31.08.2022 Projektbeschreibung des Gastgebers Professor Bohannan is a world-leading scientist in the field of microbial ecology. He has pioneered the use of biogeographical analyses as powerful tools for studying the response of microbial communities to environmental change and the resulting consequences of these responses for ecosystem functions. In Germany he continues his research at the Collaborative Research Centre “Origin and Function of Metaorganisms”.	Heimatinstitut Department of Biology University of Oregon 272 Onyx Bridge 97403 Eugene

Professor Dr. Brendan J. M. Bohannan

Fachgebiet:

Mikrobielle Ökologie und Angewandte Mikrobiologie

In Deutschland:

01.03.2022 - 31.08.2022

Projektbeschreibung des Gastgebers

Heimatinstitut

Department of Biology
University of Oregon
272 Onyx Bridge
97403 Eugene

Professorin Dr. Carmen Buchrieser
Fachgebiet: Stoffwechselphysiologie, Biochemie und Genetik der Mikroorganismen In Deutschland: 01.07.2014 - 31.07.2014 Projektbeschreibung des Gastgebers Professor Carmen Buchrieser is a leading, internationally recognized scientist in the field of infectious disease research. She developed an original and unique integrated genome-based functional approach to study bacterial pathogens. This approach has lead to major breakthroughs in our understanding how a bacterial pathogen may evolve from the environment. In Germany Professor Buchrieser will expand her approach to include proteome-based analyses of post-translational modifications of host proteins by intracellular bacterial pathogens.	Heimatinstitut Biology of Intracellular Bacteria Unit Institut Pasteur Paris 28, rue du Docteur Roux 75724 Pairs Cedex 15

Professorin Dr. Carmen Buchrieser

Fachgebiet:

Stoffwechselphysiologie, Biochemie und Genetik der Mikroorganismen

In Deutschland:

01.07.2014 - 31.07.2014

Projektbeschreibung des Gastgebers

Heimatinstitut

Biology of Intracellular Bacteria Unit
Institut Pasteur Paris
28, rue du Docteur Roux
75724 Pairs Cedex 15

Professorin Dr. Emmanuelle Marie Charpentier
Fachgebiet: Stoffwechselphysiologie, Biochemie und Genetik der Mikroorganismen In Deutschland: 01.01.2014 - Projektbeschreibung des Gastgebers Emmanuelle Charpentier gilt als eine der innovativsten Forscherinnen auf dem Gebiet der RNA-Regulation und der molekularbiologischen Infektionsforschung. Zu ihren vielbeachteten Arbeiten gehört beispielsweise die Erforschung bakterieller Krankheitserreger sowie die Fähigkeit von Bakterien, sich ihrerseits gegen Krankheitserreger zu verteidigen. An der Medizinischen Hochschule Hannover sowie am Helmholtz-Zentrum für Infektionsforschung soll sie Grundlagenforschung zu den molekularen Mechanismen mit der Umsetzung in klinische Therapien verbinden und die in Deutschland zuletzt vernachlässigte klinische Infektiologie stärken.	Heimatinstitut Max-Planck-Forschungsstelle für die Wissenschaft der Pathogene Charitéplatz 1 10117 Berlin

Professorin Dr. Emmanuelle Marie Charpentier

Fachgebiet:

Stoffwechselphysiologie, Biochemie und Genetik der Mikroorganismen

In Deutschland:

01.01.2014 -

Projektbeschreibung des Gastgebers

Heimatinstitut

Max-Planck-Forschungsstelle für die Wissenschaft der Pathogene
Charitéplatz 1
10117 Berlin

Professor Dr. David Alexander Clark
Fachgebiet: Immunologie In Deutschland: 01.03.2003 - 30.09.2003 Projektbeschreibung des Gastgebers Professor Clark has been among the pioneers in the field of reproductive immunology. His contributions to this research area include the establishment of mouse models which are currently used worldwide. Furthermore, data rising under his supervision spearheaded the understanding of growth factors and the importance of immune- vascular communication during pregnancy. Professor Clark is going to pursue a research project at the Humboldt University Berlin, in cooperation with Dr. Petra Arck. This project investigates the role of indoleamine dioxygenase and the mechanism of fetal allograft rejection in stress-induced infertility.	Heimatinstitut Department of Medicine McMaster University 1200 Main Street West, HSC-3V46 L8N 3Z5 Hamilton

Professor Dr. David Alexander Clark

Fachgebiet:

Immunologie

In Deutschland:

01.03.2003 - 30.09.2003

Projektbeschreibung des Gastgebers

Heimatinstitut

Department of Medicine
McMaster University
1200 Main Street West, HSC-3V46
L8N 3Z5 Hamilton

Professor Dr. R. John Collier
Fachgebiet: Stoffwechselphysiologie, Biochemie und Genetik der Mikroorganismen In Deutschland: 01.07.2011 - 31.07.2011 Projektbeschreibung des Gastgebers Prof. R. John Collier has contributed outstanding work in microbiology on the elucidation of mechanisms whereby bacterial protein toxins attack eukaryotic target cells and cause disease of mammalian hosts. He has done pioneering studies on the mode of action and structure of diphtheria toxin and anthrax toxin, which were groundbreaking for understanding of the molecular mechanism of many toxins and allowed design of immunotoxins against cancer and development of novel types of vaccines. During his stay in Germany at the Institute of Experimental and Clinical Pharmacology and Toxicology in Freiburg, he will study the role of cytosolic factors involved in toxin up-take.	Heimatinstitut Department of Microbiology and Immunobiology Harvard Medical School 77 Avenue Louis Pasteur, NRB 950 02115 Boston

Professor Dr. R. John Collier

Fachgebiet:

Stoffwechselphysiologie, Biochemie und Genetik der Mikroorganismen

In Deutschland:

01.07.2011 - 31.07.2011

Projektbeschreibung des Gastgebers

Heimatinstitut

Department of Microbiology and Immunobiology
Harvard Medical School
77 Avenue Louis Pasteur, NRB 950
02115 Boston

Professor Dr. Richard William Compans
Fachgebiet: Virologie In Deutschland: 01.04.1999 - 30.09.1999	Heimatinstitut Department of Microbiology & Immunology Emory University 201 Dowman Drive 30322 Atlanta

Professor Dr. Richard William Compans

Fachgebiet:

Virologie

In Deutschland:

01.04.1999 - 30.09.1999

Heimatinstitut

Department of Microbiology & Immunology
Emory University
201 Dowman Drive
30322 Atlanta

Professor Dr. Edwin L. Cooper
Fachgebiet: Immunologie In Deutschland: 01.07.2005 - 31.07.2005 Projektbeschreibung des Gastgebers Prof. Edwin Cooper is one of the leading experts in innate immunity in invertebrates. He in fact is credited with having established the discipline of "Comparative Immunology". Because of him, the analysis of ancient defensive weapons of multicellular organisms has moved to centre stage in immunology. In studying the immune system in earthworms Professor Cooper was first to show that when skin grafts are exchanged between earthworms they are rejected. He was first to identify some of the molecules involved including antimicrobial peptides. He has found that earthworm immune cells, responsible for graft rejection, will also kill human cancer cells. Finally, he has developed an exciting model using the earthworm¿s immune system for making predictions about risks to environmental hazards and public health.	Heimatinstitut Medical Center, Department of Neurobiology University of California, Los Angeles (UCLA) 10833 Le Conte Avenue 90095 Los Angeles

Professor Dr. Edwin L. Cooper

Fachgebiet:

Immunologie

In Deutschland:

01.07.2005 - 31.07.2005

Projektbeschreibung des Gastgebers

Heimatinstitut

Medical Center, Department of Neurobiology
University of California, Los Angeles (UCLA)
10833 Le Conte Avenue
90095 Los Angeles

Professor Dr. Bryan R. Cullen
Fachgebiet: Virologie In Deutschland: 01.07.1995 - 31.07.1995	Heimatinstitut Department of Molecular Genetics and Microbiology Duke University 27707 Durham

Professor Dr. Bryan R. Cullen

Fachgebiet:

Virologie

In Deutschland:

01.07.1995 - 31.07.1995

Heimatinstitut

Department of Molecular Genetics and Microbiology
Duke University
27707 Durham

Professor Dr. Arnold L. Demain
Fachgebiet: Stoffwechselphysiologie, Biochemie und Genetik der Mikroorganismen In Deutschland: 01.02.1991 - 28.02.1991	Heimatinstitut Charles A. Dana Research Institute (R.I.S.E.) Drew University HS-330 07940 Madison

Professor Dr. Arnold L. Demain

Fachgebiet:

Stoffwechselphysiologie, Biochemie und Genetik der Mikroorganismen

In Deutschland:

01.02.1991 - 28.02.1991

Heimatinstitut

Charles A. Dana Research Institute (R.I.S.E.)
Drew University
HS-330
07940 Madison

Dr. Jean Francois Dubremetz
Fachgebiet: Stoffwechselphysiologie, Biochemie und Genetik der Mikroorganismen In Deutschland: 01.08.1999 - 30.09.1999	Heimatinstitut UMR5235 DIMNP Universite de Montpellier Place Eugène Bataillon 34095 Montpellier

Dr. Jean Francois Dubremetz

Fachgebiet:

Stoffwechselphysiologie, Biochemie und Genetik der Mikroorganismen

In Deutschland:

01.08.1999 - 30.09.1999

Heimatinstitut

UMR5235 DIMNP
Universite de Montpellier
Place Eugène Bataillon
34095 Montpellier

Professor Dr. Christian Frezza
Fachgebiet: Stoffwechselphysiologie, Biochemie und Genetik der Mikroorganismen In Deutschland: 01.10.2021 -	Heimatinstitut Universität zu Köln Albertus-Magnus-Platz 50931 Köln

Professor Dr. Christian Frezza

Fachgebiet:

Stoffwechselphysiologie, Biochemie und Genetik der Mikroorganismen

In Deutschland:

01.10.2021 -

Heimatinstitut

Universität zu Köln
Albertus-Magnus-Platz
50931 Köln

Professor Dr. Robin B. Gasser
Fachgebiet: Medizinische Mikrobiologie und Mykologie und Hygiene, Molekulare Infektionsbiologie In Deutschland: 01.02.2014 - 30.04.2014 Projektbeschreibung des Gastgebers Professor Gasser is one of the global leaders in the field of molecular veterinary parasitology. His scientific contributions have led to cutting-edge molecular, genomic and bioinformatic technologies which provided novel diagnostic methods and intervention strategies against numerous important parasites. The collaborative research program in Germany will contribute to the development of new post-genomic biotechnological solutions alleviating human and animal suffering caused by destructive pathogens.	Heimatinstitut Department of Veterinary Science University of Melbourne Corner Park Drive and Flemington Road, Parkville, Victoria 3010 University Of Melbourne

Professor Dr. Robin B. Gasser

Fachgebiet:

Medizinische Mikrobiologie und Mykologie und Hygiene, Molekulare Infektionsbiologie

In Deutschland:

01.02.2014 - 30.04.2014

Projektbeschreibung des Gastgebers

Heimatinstitut

Department of Veterinary Science
University of Melbourne
Corner Park Drive and Flemington Road, Parkville, Victoria
3010 University Of Melbourne

Professor Dr. Michael S. Gilmore
Fachgebiet: Stoffwechselphysiologie, Biochemie und Genetik der Mikroorganismen In Deutschland: 01.06.2007 - 30.06.2007 Projektbeschreibung des Gastgebers Professor Gilmore is awarded the Humboldt Award for his achievements in the analysis of microbial pathogens. He was one of the first scientists who described enterococci as infectious agents with strong impact on nosocomial infections. He analyzed the disease-related mechanisms of these particular pathogens and was able to set up strategies to combat these infectious agents. Thus, Professor Gilmore belongs to the leading scientists worldwide working on the analysis of nosocomial infectious agents.	Heimatinstitut Massachusetts Eye & Ear Infirmary Harvard Medical School 243 Charles St. 02114 Boston

Professor Dr. Michael S. Gilmore

Fachgebiet:

Stoffwechselphysiologie, Biochemie und Genetik der Mikroorganismen

In Deutschland:

01.06.2007 - 30.06.2007

Projektbeschreibung des Gastgebers

Heimatinstitut

Massachusetts Eye & Ear Infirmary
Harvard Medical School
243 Charles St.
02114 Boston

Professor Dr. Seyed Ehtesham Hasnain
Fachgebiet: Stoffwechselphysiologie, Biochemie und Genetik der Mikroorganismen In Deutschland: 01.09.2018 - 30.09.2018 Projektbeschreibung des Gastgebers Professor Hasnain is well known internationally for his outstanding research on the analyses of infectious diseases due to bacteria. He has made important contributions to the pathogenicity and epidemiology of Mycobacterium tuberculosis. Beside the development of methods to rapidly detect and type bacterial pathogens, especially mycobacteria, he identified new antigenic substances of M. tuberculosis which represent promising vaccine candidates against mycobacteria. In Germany, he continues his research on the population structure and genome content of pathogenic bacteria, especially Escherichia coli and staphylocci.	Heimatinstitut Institute of Molecular Medicine Jamia Hamdard University Guru Ravidas Marg, Tughlakabad 110062 South West Delhi

Professor Dr. Seyed Ehtesham Hasnain

Fachgebiet:

Stoffwechselphysiologie, Biochemie und Genetik der Mikroorganismen

In Deutschland:

01.09.2018 - 30.09.2018

Projektbeschreibung des Gastgebers

Heimatinstitut

Institute of Molecular Medicine
Jamia Hamdard University
Guru Ravidas Marg, Tughlakabad
110062 South West Delhi

Professor Dr. Karl Erik Hellstroem
Fachgebiet: Immunologie In Deutschland: 16.09.1980 - 15.07.1981	Heimatinstitut Tumorimmunology Pacific Northwest Research Institute 720 Broadway 98122 Seattle

Professor Dr. Karl Erik Hellstroem

Fachgebiet:

Immunologie

In Deutschland:

16.09.1980 - 15.07.1981

Heimatinstitut

Tumorimmunology
Pacific Northwest Research Institute
720 Broadway
98122 Seattle

Professorin Dr. Ingegerd Hellstroem
Fachgebiet: Immunologie In Deutschland: 16.09.1980 - 15.07.1981	Heimatinstitut Tumorimmunology Pacific Northwest Research Institute 720 Broadway 98122 Seattle

Professorin Dr. Ingegerd Hellstroem

Fachgebiet:

Immunologie

In Deutschland:

16.09.1980 - 15.07.1981

Heimatinstitut

Tumorimmunology
Pacific Northwest Research Institute
720 Broadway
98122 Seattle

Professor Dr. Jules Alphonse Hoffmann
Fachgebiet: Immunologie In Deutschland: 01.08.1984 - 31.01.1985	Heimatinstitut Institut de Biologie Moleculaire et Cellulaire, UPR 9002 Universite de Strasbourg 15 Rue Rene Descartes 67000 Strasbourg

Professor Dr. Jules Alphonse Hoffmann

Fachgebiet:

Immunologie

In Deutschland:

01.08.1984 - 31.01.1985

Heimatinstitut

Institut de Biologie Moleculaire et Cellulaire, UPR 9002
Universite de Strasbourg
15 Rue Rene Descartes
67000 Strasbourg

Professor Dr. Fumio Inagaki
Fachgebiet: Mikrobielle Ökologie und Angewandte Mikrobiologie In Deutschland: 01.07.2024 - 30.09.2024	Heimatinstitut Project Team for Ocean Basalt CCS Basic Research, General Project Team for SIP Japan Agency for Marine-Earth Science and Technology Showa-machi 3173-25, Kanazawa-ku 236-0001 Yokohama Gastinstitut in Deutschland Prof. Dr. Kai-Uwe Hinrichs Zentrum für Marine Umweltwissenschaften (MARUM) Universität Bremen Leobener Straße 28359 Bremen

Professor Dr. Fumio Inagaki

Fachgebiet:

Mikrobielle Ökologie und Angewandte Mikrobiologie

In Deutschland:

01.07.2024 - 30.09.2024

Heimatinstitut

Project Team for Ocean Basalt CCS Basic Research, General Project Team for SIP
Japan Agency for Marine-Earth Science and Technology
Showa-machi 3173-25, Kanazawa-ku
236-0001 Yokohama

Gastinstitut in Deutschland

Prof. Dr. Kai-Uwe Hinrichs
Zentrum für Marine Umweltwissenschaften (MARUM)
Universität Bremen
Leobener Straße
28359 Bremen

Dr. Ilesh Vinodrai Jani
Fachgebiet: Immunologie In Deutschland: 02.11.2018 - 02.11.2018	Heimatinstitut Instituto Nacional de Saude Av. Eduardo Monoplane 1008, 2nd floor Maputo

Dr. Ilesh Vinodrai Jani

Fachgebiet:

Immunologie

In Deutschland:

02.11.2018 - 02.11.2018

Heimatinstitut

Instituto Nacional de Saude
Av. Eduardo Monoplane 1008, 2nd floor
Maputo

Professor Dr. Jens Christian Jensenius
Fachgebiet: Immunologie In Deutschland: 01.03.2004 - 31.05.2004 Projektbeschreibung des Gastgebers The pioneering scientific contribution of Professor Jensenius is the molecular characterization of a new anti-micorbial system in innate immune defense. This so-called lectin pathway of complement activations is initiated by serum molecules recognizing sugars displayed on microorganisms but also on tumor cells. Genetically determined deficiency in theses defense molecules predisposes for infections. Since the may also play an important role in tumor defense we will investigate whether these molecules could present a therapeutic modality for tumor patients with such deficiency.	Heimatinstitut Department of Medical Microbiology and Immunology Aarhus University 8000 Aarhus

Professor Dr. Jens Christian Jensenius

Fachgebiet:

Immunologie

In Deutschland:

01.03.2004 - 31.05.2004

Projektbeschreibung des Gastgebers

Heimatinstitut

Department of Medical Microbiology and Immunology
Aarhus University
8000 Aarhus

Professor Dr. Nicolai V. Kaverin
Fachgebiet: Virologie In Deutschland: 01.04.1998 - 30.06.1998	Heimatinstitut Ivanovsky Institute of Virology Russian Academy of Medical Sciences Gamaleya St. 16 123098 Moscow

Professor Dr. Nicolai V. Kaverin

Fachgebiet:

Virologie

In Deutschland:

01.04.1998 - 30.06.1998

Heimatinstitut

Ivanovsky Institute of Virology
Russian Academy of Medical Sciences
Gamaleya St. 16
123098 Moscow

Professor Dr. Jay Keasling
Fachgebiet: Stoffwechselphysiologie, Biochemie und Genetik der Mikroorganismen In Deutschland: 01.03.2024 - 30.04.2024 Projektbeschreibung des Gastgebers Professor Keasling is a pioneer in the field of synthetic biology. He is known for engineering microbial metabolism to generate robust hosts able to produce valuable compounds, such as biofuels, commodity chemicals, and pharmaceuticals, under various industrial conditions for a broad range of applications. His latest work on natural product synthesis allows the conversion of simple renewable resources into molecules dearly required in the pharma industry. In Germany, Professor Keasling focuses on optimizing strategies, especially on the terpenoid synthesis and metabolic engineering of pseudomonas as host organisms.	Heimatinstitut The Joint BioEnergy Institute University of California, Berkeley 5885 Hollis Street, 4th Floor 94608 Emeryville, CA

Professor Dr. Jay Keasling

Fachgebiet:

Stoffwechselphysiologie, Biochemie und Genetik der Mikroorganismen

In Deutschland:

01.03.2024 - 30.04.2024

Projektbeschreibung des Gastgebers

Heimatinstitut

The Joint BioEnergy Institute
University of California, Berkeley
5885 Hollis Street, 4th Floor
94608 Emeryville, CA

Dr. Alan P. Kendal
Fachgebiet: Virologie In Deutschland: 01.09.1989 - 31.08.1990	Heimatinstitut Emory University Grace C. Rollins Bldg., Room 256 30322 Atlanta

Dr. Alan P. Kendal

Fachgebiet:

Virologie

In Deutschland:

01.09.1989 - 31.08.1990

Heimatinstitut

Emory University
Grace C. Rollins Bldg., Room 256
30322 Atlanta

Professor Dr. Jay T. Lennon
Fachgebiet: Mikrobielle Ökologie und Angewandte Mikrobiologie In Deutschland: 01.07.2023 - 31.12.2023 Projektbeschreibung des Gastgebers Professor Lennon is an international leader in the field of microbial evolution and ecology. He has made ground-breaking contributions towards the conceptual understanding of dormancy, which describes the ability of individuals to enter a state of low metabolic activity, shielding them from their environment. In Germany, Professor Lennon will continue his interdisciplinary research approach towards dormancy, including mathematical modeling and theory building.	Heimatinstitut Department of Biology Indiana University 1001 East 3rd St. 47405 Bloomington

Professor Dr. Jay T. Lennon

Fachgebiet:

Mikrobielle Ökologie und Angewandte Mikrobiologie

In Deutschland:

01.07.2023 - 31.12.2023

Projektbeschreibung des Gastgebers

Heimatinstitut

Department of Biology
Indiana University
1001 East 3rd St.
47405 Bloomington

Professor Dr. Christopher Linington
Fachgebiet: Immunologie In Deutschland: 01.01.2016 - 30.04.2016 Projektbeschreibung des Gastgebers Professor Linington is an outstanding and internationally recognized neuroimmunologist. He made significant contributions to the role of B cells and autoantibodies in demyelinating diseases of the central nervous system. Prof. Linington discovered myelin oligodendrocyte glycoprotein as the major target in animal models of multiple sclerosis. Collectively, these discoveries and the conceptual framework formulated by Prof. Linington led to the therapeutic targeting of B cells in multiple sclerosis. The clinical results of such therapeutic trials are so far impressive and, in all likelihood, phase III trials using B-cell-depleting monoclonal antibodies will provide the next major therapeutic progress for multiple sclerosis. He further discovered the role of pathogenic antibodies against neuronal structures in multiple sclerosis.	Heimatinstitut Infection, Immunity and Inflammation University of Glasgow 120 University Place G12 8TA Glasgow

Professor Dr. Christopher Linington

Fachgebiet:

Immunologie

In Deutschland:

01.01.2016 - 30.04.2016

Projektbeschreibung des Gastgebers

Heimatinstitut

Infection, Immunity and Inflammation
University of Glasgow
120 University Place
G12 8TA Glasgow

Professor Dr. Hugo Daniel Lujan
Fachgebiet: Medizinische Mikrobiologie und Mykologie und Hygiene, Molekulare Infektionsbiologie In Deutschland: 01.02.2024 - 30.04.2024 Projektbeschreibung des Gastgebers Professor Lujan is an international authority in the study of the molecular basis of cellular differentiation and adaptation of early-branching eukaryotic organisms, in particular of those acting as human pathogens. Professor Lujan has discovered the molecular mechanism controlling antigenic variation in the intestinal parasite Giardia lamblia, was able to disrupt this process that allows the microorganism to avoid the immune response of its hosts and developed the first oral vaccine composed solely of surface antigens of Giardia. Since these proteins protect the parasite in the harsh environment of the upper intestinal tract and since they are highly immunogenic, Professor Lujan designed an oral vaccine platform composed by Virus-like Particles covered with those Giardia molecules to deliver vaccinal antigens by the oral route. In Germany, he continues his research on the development of oral vaccines against Mycobacterium tuberculosis and other respiratory pathogens.	Heimatinstitut Centro de Investigacion y Desarrollo en Inmunologia y Enfermedades Infecciosas (CIDIE-CONICET) Universidad Catolica de Cordoba Av. Armada Argentina 3555 X5016DHK Cordoba

Professor Dr. Hugo Daniel Lujan

Fachgebiet:

Medizinische Mikrobiologie und Mykologie und Hygiene, Molekulare Infektionsbiologie

In Deutschland:

01.02.2024 - 30.04.2024

Projektbeschreibung des Gastgebers

Heimatinstitut

Centro de Investigacion y Desarrollo en Inmunologia y Enfermedades Infecciosas (CIDIE-CONICET)
Universidad Catolica de Cordoba
Av. Armada Argentina 3555
X5016DHK Cordoba

Professor Dr. Luciano Marraffini
Fachgebiet: Mikrobielle Ökologie und Angewandte Mikrobiologie In Deutschland: 02.12.2020 - 02.12.2020	Heimatinstitut Laboratory of Bacteriology Rockefeller University 1230 York Avenue 10065 New York

Professor Dr. Luciano Marraffini

Fachgebiet:

Mikrobielle Ökologie und Angewandte Mikrobiologie

In Deutschland:

02.12.2020 - 02.12.2020

Heimatinstitut

Laboratory of Bacteriology
Rockefeller University
1230 York Avenue
10065 New York

Professor Dr. Mark Christopher Marsh
Fachgebiet: Virologie In Deutschland: 01.10.2008 - 31.10.2008	Heimatinstitut MRC-LMCB University College London (UCL) Gower Street WC1E 6BT London

Professor Dr. Mark Christopher Marsh

Fachgebiet:

Virologie

In Deutschland:

01.10.2008 - 31.10.2008

Heimatinstitut

MRC-LMCB
University College London (UCL)
Gower Street
WC1E 6BT London

Professor Dr. Jerry R. McGhee
Fachgebiet: Immunologie In Deutschland: 16.03.1986 - 15.10.1986	Heimatinstitut Department of Microbiology University of Alabama at Birmingham Bevill Biomedical Research Bldg., Room 761A, 845 19th Street South 35294-2170 Birmingham

Professor Dr. Jerry R. McGhee

Fachgebiet:

Immunologie

In Deutschland:

16.03.1986 - 15.10.1986

Heimatinstitut

Department of Microbiology
University of Alabama at Birmingham
Bevill Biomedical Research Bldg., Room 761A, 845 19th Street South
35294-2170 Birmingham

Professor Dr. Opendra Narayan
Fachgebiet: Virologie In Deutschland: 01.06.1990 - 31.08.1990	Heimatinstitut Medical Center/Department of Microbiology University of Kansas 66160 Kansas City

Professor Dr. Opendra Narayan

Fachgebiet:

Virologie

In Deutschland:

01.06.1990 - 31.08.1990

Heimatinstitut

Medical Center/Department of Microbiology
University of Kansas
66160 Kansas City

Professor Dr. Sergei Nedospasov
Fachgebiet: Immunologie In Deutschland: 01.02.2006 - 31.01.2007 Projektbeschreibung des Gastgebers Prof. Sergei Nedospasov is a molecular biologist working in the field of immunology. He was the first to clone chromosomal genes for tumor necrosis factor (TNF) and lymphotoxin both in humans and mice, and to establish link of these genes to the MHC-gene. Prof. Nedospasov's lab generated unique panels of knockout and transgenic mice allowing to study the physiological role of TNF and lymphotoxin in vivo. His contribution to the field of cancer is based on identification of several human cancer antigens. Prof. Nedospasov's proposed research in Germany will concern the role of TNF in cancer.	Heimatinstitut Engelhardt Institute of Molecular Biology Russian Academy of Sciences 32, Vavilov str. 119991 Moscow

Professor Dr. Sergei Nedospasov

Fachgebiet:

Immunologie

In Deutschland:

01.02.2006 - 31.01.2007

Projektbeschreibung des Gastgebers

Heimatinstitut

Engelhardt Institute of Molecular Biology
Russian Academy of Sciences
32, Vavilov str.
119991 Moscow

Professor Dr. Shin-Ichi Nishikawa
Fachgebiet: Immunologie In Deutschland: 01.06.2003 - 30.06.2003	Heimatinstitut Stem Cell Research Group RIKEN Center for Biosystems Dynamics Research (BDR) Minatojima Minamicho 2-2-3, Chuo-ku 650-0047 Kobe

Professor Dr. Shin-Ichi Nishikawa

Fachgebiet:

Immunologie

In Deutschland:

01.06.2003 - 30.06.2003

Heimatinstitut

Stem Cell Research Group
RIKEN Center for Biosystems Dynamics Research (BDR)
Minatojima Minamicho 2-2-3, Chuo-ku
650-0047 Kobe

Professorin Dr. Francine Ntoumi
Fachgebiet: Medizinische Mikrobiologie und Mykologie und Hygiene, Molekulare Infektionsbiologie In Deutschland: 01.07.2021 - 30.06.2026 Projektbeschreibung des Gastgebers Dr. Francine Ntoumi from the Universite Marien Ngouabi, Brazzaville, Kongo. Dr. Francine Ntoumi is internationally recognised for her leadership in developing and conducting health research in Africa. She has been recognised as the best African female scientist in 2012 by the African Union and received the prestigious Kwma Nkrumah award of the continent. In her research project she will focus on evaluating the impact of malaria intermittent preventive treatment in Congolese pregnant women living in an area of high parasite resistance for sulfadoxine-pyrimethamine. Dr. Ntoumi is hosted by Professor Peter Kremsner at the University of Tuebingen.	Heimatinstitut Faculté des Sciences de la Santé Universite Marien Ngouabi Fondation Congolaise pour la Recherche Medicale Brazzaville Gastinstitut in Deutschland Prof. Dr. Francine Ntoumi Faculté des Sciences de la Santé Universite Marien Ngouabi Fondation Congolaise pour la Recherche Medicale Brazzaville Véronique Nintchom Penlap Beng University of Yaounde 8511 Yaounde Prof. Dr. Steffen Borrmann Institut für Tropenmedizin Eberhard Karls Universität Tübingen Wilhelmstraße 27 72074 Tübingen

Professorin Dr. Francine Ntoumi

Fachgebiet:

Medizinische Mikrobiologie und Mykologie und Hygiene, Molekulare Infektionsbiologie

In Deutschland:

01.07.2021 - 30.06.2026

Projektbeschreibung des Gastgebers

Heimatinstitut

Faculté des Sciences de la Santé
Universite Marien Ngouabi
Fondation Congolaise pour la Recherche Medicale
Brazzaville

Gastinstitut in Deutschland

Prof. Dr. Francine Ntoumi
Faculté des Sciences de la Santé
Universite Marien Ngouabi
Fondation Congolaise pour la Recherche Medicale
Brazzaville

Véronique Nintchom Penlap Beng
University of Yaounde
8511 Yaounde

Prof. Dr. Steffen Borrmann
Institut für Tropenmedizin
Eberhard Karls Universität Tübingen
Wilhelmstraße 27
72074 Tübingen

Professorin Dr. Faith H. A. Osier
Fachgebiet: Medizinische Mikrobiologie und Mykologie und Hygiene, Molekulare Infektionsbiologie In Deutschland: 01.11.2016 - 31.12.2020	Heimatinstitut Faculty of Natural Sciences Department of Life Sciences Imperial College London South Kensingtion Campus SW7 2AZ London

Professorin Dr. Faith H. A. Osier

Fachgebiet:

Medizinische Mikrobiologie und Mykologie und Hygiene, Molekulare Infektionsbiologie

In Deutschland:

01.11.2016 - 31.12.2020

Heimatinstitut

Faculty of Natural Sciences Department of Life Sciences
Imperial College London
South Kensingtion Campus
SW7 2AZ London

Professor Dr. Wade P. Parks
Fachgebiet: Virologie In Deutschland: 01.09.1997 - 30.11.1997	Heimatinstitut Departments of Pediatrics and Microbiology New York University NBV 8 8S7, 462 First Avenue 10016 New York

Professor Dr. Wade P. Parks

Fachgebiet:

Virologie

In Deutschland:

01.09.1997 - 30.11.1997

Heimatinstitut

Departments of Pediatrics and Microbiology
New York University
NBV 8 8S7, 462 First Avenue
10016 New York

Professor Dr. B. Matija Peterlin
Fachgebiet: Immunologie In Deutschland: 01.09.1996 - 30.11.1996	Heimatinstitut Howard Hughes Medical Institute University of California, San Francisco 3rd & Parnassus Avenues U426, Box 0703 94143-0703 San Francisco

Professor Dr. B. Matija Peterlin

Fachgebiet:

Immunologie

In Deutschland:

01.09.1996 - 30.11.1996

Heimatinstitut

Howard Hughes Medical Institute
University of California, San Francisco
3rd & Parnassus Avenues U426, Box 0703
94143-0703 San Francisco

Professor Dr. Richard A. Proctor
Fachgebiet: Medizinische Mikrobiologie und Mykologie und Hygiene, Molekulare Infektionsbiologie In Deutschland: 01.09.1995 - 31.08.1996	Heimatinstitut Department of Medical Microbiology and Immunology University of Wisconsin-Madison 825 Blackfriars Loop 27519 Cary

Professor Dr. Richard A. Proctor

Fachgebiet:

Medizinische Mikrobiologie und Mykologie und Hygiene, Molekulare Infektionsbiologie

In Deutschland:

01.09.1995 - 31.08.1996

Heimatinstitut

Department of Medical Microbiology and Immunology
University of Wisconsin-Madison
825 Blackfriars Loop
27519 Cary

Professor Dr. Gustaaf Frank Rimmelzwaan
Fachgebiet: Virologie In Deutschland: 01.01.2023 - Projektbeschreibung des Gastgebers Guus F. Rimmelzwaan arbeitet an der Schnittstelle zwischen Human- und Tiermedizin. Er gilt als international profilierter Virus-Immunologe, sein Spezialgebiet ist die immunologische Forschung zu Influenzaviren. Viren also, die bei Mensch wie Tier auftreten und die potenziell auch von Tier zu Mensch und umgekehrt übertragbar sind. So hat Rimmelzwaan intensiv zur Vogelgrippe geforscht. Weitere Themen seiner bisherigen Arbeiten waren beispielsweise die Rolle von Katzen als mögliche Überträger von Influenzaviren auf Menschen. Besonderes Renommee hat Rimmelzwaan mit seinen Forschungen zu den T-Zellen des Immunsystems erlangt: Er konnte die Bedeutung dieser Gruppe der weißen Blutzellen für einen breiteren Schutz gegen verschiedene Influenzaviren nachweisen. Eine Erkenntnis, die für die Festlegung von Impfstrategien und die Entwicklung neuer Impfstoffe gleichermaßen relevant ist: Ein Impfschutz gegen möglichst viele verschiedene Varianten ist gerade bei den Influenzaviren von Vorteil, da diese besonders wandlungsfähig sind. Als Alexander von Humboldt-Professor soll Guus F. Rimmelzwaan die Stiftung Tierärztliche Hochschule Hannover (TiHo) in der Immunologie und der Gesundheitsforschung stärker international etablieren. Zugleich fügt sich die Humboldt-Professur bestens in den One Health-Gedanken ein, den die TiHo strategisch verfolgt: Menschliche und tierische Gesundheit werden bis auf Ebene des Ökosystems gemeinsam betrachtet.	Heimatinstitut Research Center for Emerging Infections and Zoonoses Stiftung Tierärztliche Hochschule Hannover Bünteweg 17 30559 Hannover

Professor Dr. Gustaaf Frank Rimmelzwaan

Fachgebiet:

Virologie

In Deutschland:

01.01.2023 -

Projektbeschreibung des Gastgebers

Heimatinstitut

Research Center for Emerging Infections and Zoonoses
Stiftung Tierärztliche Hochschule Hannover
Bünteweg 17
30559 Hannover

Dr. Torben Schiffner
Fachgebiet: Immunologie In Deutschland: 01.12.2020 - 31.12.2024	Heimatinstitut Immunology The Scripps Research Institute 9365 Waples Street, Suite E, R203 92121 San Diego Gastinstitut in Deutschland Prof. Dr. Jens Meiler Institut für Wirkstoffentwicklung Universität Leipzig Liebigstr. 19 04103 Leipzig

Dr. Torben Schiffner

Fachgebiet:

Immunologie

In Deutschland:

01.12.2020 - 31.12.2024

Heimatinstitut

Immunology
The Scripps Research Institute
9365 Waples Street, Suite E, R203
92121 San Diego

Gastinstitut in Deutschland

Prof. Dr. Jens Meiler
Institut für Wirkstoffentwicklung
Universität Leipzig
Liebigstr. 19
04103 Leipzig

Professor Dr. Joachim L. W. Schultze
Fachgebiet: Immunologie In Deutschland: 01.11.2001 - 31.10.2005 Projektbeschreibung des Gastgebers Dr. Schultze is clearly one of the leading young scientist in his field of research focusing on the immunology and immunotherapy of cancer with a particular focus on hematologic malignancies. He studied medicine at the University of Tuebingen where he already started his work in immunology. Under the directions of Professor Berg he performed his doctoral thesis about the influence of certain lectins on the immune response of cancer patients. Dr. Schultze joined the laboratory of Professor Lee Nadler at Dana-Farber Cancer Institute, Harvard Medical School in 1993. He primarily focused on the role of the CD40-CD40L interactions and its potential to develop a novel cancer immunotherapy concept for patients with tumors derived from malignant B cells, an important cell of the immune system. Dr. Schultze is one of the rare individuals who has covered this long distance and has demonstrated that novel knowledge can be translated into clinical experiments. Based on the interaction between CD40 on the tumor cell and a CD40L signal, he has demonstrated that malignant B cells can be turned into efficient antigen presenting cells thereby stimulating the patient¿s immune system and he has recently translated this concept into a vaccine approach for patients with B cell malignancies. More recently he was one of the founding members of a team of researchers that have developed the concept of so-called universal tumor antigens. Dr. Schultze and his colleagues have demonstrated that tumor antigens exist that are expressed in the majority of all human cancer and that these targets might be used for vaccines that could be applied to the great majority of all patients with cancer. Dr. Schultze will continue this work also in Cologne. Despite these promising results Dr. Schultze and his team have established over the last years, he has always been worried by the dysfunctional immune system in cancer patients. For years he studied the functional defects in patients with lymphoma without being able to pin point the exact mechanisms. Similar results have been reported for most other cancers such as colon cancer or breast cancer. It seemed that the classical hypothesis driven approach would not lead to an answer in this critical area of cancer research. There is no doubt that any kind of active immunotherapy will only be successful if immune defects can be overcome. To address this important question Dr. Schultze has now proposed to merge two fields of research, namely the functional and immunological characterization of T cells in cancer patient with the new molecular approach of gene expression profiling. This is the central theme of his research supported by the Sofja-Kovalevskaja award. He proposes to define gene clusters or marker genes that will lead to the signalling pathways involved in T cell inhibition in cancer patients. Once identified, it will be possible to specifically determine therapeutic counterattacks.	Heimatinstitut Life and Medical Sciences Center (LIMES) Rheinische Friedrich-Wilhelms-Universität Bonn Carl-Troll-Str. 31 53115 Bonn

Professor Dr. Joachim L. W. Schultze

Fachgebiet:

Immunologie

In Deutschland:

01.11.2001 - 31.10.2005

Projektbeschreibung des Gastgebers

Dr. Schultze is clearly one of the leading young scientist in his field of research focusing on the immunology and immunotherapy of cancer with a particular focus on hematologic malignancies. He studied medicine at the University of Tuebingen where he already started his work in immunology. Under the directions of Professor Berg he performed his doctoral thesis about the influence of certain lectins on the immune response of cancer patients.
Dr. Schultze joined the laboratory of Professor Lee Nadler at Dana-Farber Cancer Institute, Harvard Medical School in 1993. He primarily focused on the role of the CD40-CD40L interactions and its potential to develop a novel cancer immunotherapy concept for patients with tumors derived from malignant B cells, an important cell of the immune system. Dr. Schultze is one of the rare individuals who has covered this long distance and has demonstrated that novel knowledge can be translated into clinical experiments. Based on the interaction between CD40 on the tumor cell and a CD40L signal, he has demonstrated that malignant B cells can be turned into efficient antigen presenting cells thereby stimulating the patient¿s immune system and he has recently translated this concept into a vaccine approach for patients with B cell malignancies.

More recently he was one of the founding members of a team of researchers that have developed the concept of so-called universal tumor antigens. Dr. Schultze and his colleagues have demonstrated that tumor antigens exist that are expressed in the majority of all human cancer and that these targets might be used for vaccines that could be applied to the great majority of all patients with cancer. Dr. Schultze will continue this work also in Cologne.

Despite these promising results Dr. Schultze and his team have established over the last years, he has always been worried by the dysfunctional immune system in cancer patients. For years he studied the functional defects in patients with lymphoma without being able to pin point the exact mechanisms. Similar results have been reported for most other cancers such as colon cancer or breast cancer. It seemed that the classical hypothesis driven approach would not lead to an answer in this critical area of cancer research. There is no doubt that any kind of active immunotherapy will only be successful if immune defects can be overcome. To address this important question Dr. Schultze has now proposed to merge two fields of research, namely the functional and immunological characterization of T cells in cancer patient with the new molecular approach of gene expression profiling. This is the central theme of his research supported by the Sofja-Kovalevskaja award. He proposes to define gene clusters or marker genes that will lead to the signalling pathways involved in T cell inhibition in cancer patients. Once identified, it will be possible to specifically determine therapeutic counterattacks.

Heimatinstitut

Life and Medical Sciences Center (LIMES)
Rheinische Friedrich-Wilhelms-Universität Bonn
Carl-Troll-Str. 31
53115 Bonn

Professor Dr. Michael H. Sieweke
Fachgebiet: Immunologie In Deutschland: 01.04.2023 - Projektbeschreibung des Gastgebers Unser Körper befindet sich in stetigem Wandel. In vielen Organen – sei es im Darm, in der Haut oder im Blut – bilden Stammzellen immer wieder neue Zellen. So wird das Gewebe erhalten oder nach Verletzungen regeneriert. Siewekes Spezialgebiet sind die Mechanismen, mit denen Immunzellen gebildet werden und die Rolle dieser Zellen bei der Erhaltung von Gewebefunktionen und Regeneration. Seine international anerkannte Arbeit könnte dazu beitragen, neue Ansätze bei der Zelltherapie zu entwickeln. So entdeckte Siewekes Team beispielsweise einen Notfallmechanismus, der auf schwere Infektionen zügig reagiert, indem er den Körper mit neuen Immunzellen versorgt, welche die eindringenden Krankheitserreger bekämpfen. Diese Mechanismen könnten in Zukunft bei Knochenmarktransplantationen genutzt werden, um das Immunsystem schneller wieder aufzubauen. Siewekes Forschung hat auch gezeigt, dass einige reife Immunzellen, sogenannte Makrophagen, sich unbegrenzt teilen und ihre Anzahl erhalten können, indem sie ähnliche Mechanismen benutzen wie Stammzellen. Die Hoffnung ist, dass seine Forschung dazu beitragen wird, diese Mechanismen zu aktivieren, wenn die Regeneration nicht gelingt oder größere Mengen von Makrophagen für Zelltherapien zur Verfügung zu stellen. Als Humboldt-Professor soll Sieweke die Technische Universität Dresden künftig stärker an der Schnittstelle von Immunforschung und Geweberegeneration positionieren und neue medizinische Anwendungen in diesem Bereich vorantreiben.	Heimatinstitut Center for Regenerative Therapies Dresden (CRTD) Technische Universität Dresden Fetscherstrasse 105 01307 Dresden

Professor Dr. Michael H. Sieweke

Fachgebiet:

Immunologie

In Deutschland:

01.04.2023 -

Projektbeschreibung des Gastgebers

Heimatinstitut

Center for Regenerative Therapies Dresden (CRTD)
Technische Universität Dresden
Fetscherstrasse 105
01307 Dresden

Professor Dr. Brajesh Singh
Fachgebiet: Mikrobielle Ökologie und Angewandte Mikrobiologie In Deutschland: 01.06.2022 - 31.07.2022 Projektbeschreibung des Gastgebers Professor Singh is well known internationally for his outstanding research in microbial ecology and the appreciation of microbial diversity for the functioning of terrestrial ecosystems. Professor Singh combines basic and applied research to foster sustainable development, environmental protection and food security. During his stay in Germany, he intends to study the global distribution, drivers, risks and functional role of soil biodiversity.	Heimatinstitut Hawkesbury Institute for the Environment Western Sydney University Locked Bag 1797 2751 Sydney

Professor Dr. Brajesh Singh

Fachgebiet:

Mikrobielle Ökologie und Angewandte Mikrobiologie

In Deutschland:

01.06.2022 - 31.07.2022

Projektbeschreibung des Gastgebers

Heimatinstitut

Hawkesbury Institute for the Environment
Western Sydney University
Locked Bag 1797
2751 Sydney

Professor Dr. Rotem Sorek
Fachgebiet: Stoffwechselphysiologie, Biochemie und Genetik der Mikroorganismen In Deutschland: 01.06.2024 - 31.05.2029 Projektbeschreibung des Gastgebers Professor Rotem Sorek from the Weizmann Institute of Sciences, Israel Professor Sorek is a world-leading microbiologist and has made seminal discoveries on how microbes defend themselves against phages, which are viruses of bacteria. Many of the defense systems discovered by him show unexpected similarity to the innate immune system of humans. While in Germany, Rotem Sorek and his hosts intend to identify hitherto unknown antiviral defense strategies of the human immune system with the help of bacterial anti-virus defense mechanisms, which could be used in new therapies for treating infections. Professor Sorek is hosted by Professor Jörg Vogel at the Helmholtz Institute for RNA-based Infection Research in Würzburg and Professor Veit Hornung at the Ludwig Maximilian University of Munich.	Heimatinstitut Department of Molecular Cell Biology Weizmann Institute of Science 234 Herzl Street 7610001 Rehovot Gastinstitut in Deutschland Prof. Dr. Veit Hornung Genzentrum Ludwig-Maximilians-Universität München (LMU) Feodor-Lynen-Straße 25 81377 München Prof. Dr. Jörg Vogel Helmholtz Institut für RNA-basierte Infektionsforschung (HIRI) Josef-Schneider-Straße 2, Gebäude D15 97080 Würzburg

Professor Dr. Rotem Sorek

Fachgebiet:

Stoffwechselphysiologie, Biochemie und Genetik der Mikroorganismen

In Deutschland:

01.06.2024 - 31.05.2029

Projektbeschreibung des Gastgebers

Heimatinstitut

Department of Molecular Cell Biology
Weizmann Institute of Science
234 Herzl Street
7610001 Rehovot

Gastinstitut in Deutschland

Prof. Dr. Veit Hornung
Genzentrum
Ludwig-Maximilians-Universität München (LMU)
Feodor-Lynen-Straße 25
81377 München

Prof. Dr. Jörg Vogel
Helmholtz Institut für RNA-basierte Infektionsforschung (HIRI)
Josef-Schneider-Straße 2, Gebäude D15
97080 Würzburg

Professor Dr. Mark F. Stinski
Fachgebiet: Virologie In Deutschland: 01.03.1991 - 31.08.1991	Heimatinstitut Department of Microbiology University of Iowa 3-403 BSB, 51 Newton Road 52242 Iowa City

Professor Dr. Mark F. Stinski

Fachgebiet:

Virologie

In Deutschland:

01.03.1991 - 31.08.1991

Heimatinstitut

Department of Microbiology
University of Iowa
3-403 BSB, 51 Newton Road
52242 Iowa City

Professor Dr. Rainer F. Storb

Fachgebiet:

Immunologie

In Deutschland:

16.08.1977 - 15.09.1977

Heimatinstitut

Transplantation Biology
Fred Hutchinson Cancer Research Center
1100 Fairview Avenue North, D1-100
98109-1024 Seattle

Professor Dr. Takeshi Tsubata

Fachgebiet:

Immunologie

In Deutschland:

01.09.2010 - 30.09.2010

Heimatinstitut

Department of Pathology
Nihon University School of Dentistry
1-8-13, Kanda-Surugadai, Chiyoda-ku
101-8310 Tokyo

Dr. Athanasios Typas

Fachgebiet:

Stoffwechselphysiologie, Biochemie und Genetik der Mikroorganismen

In Deutschland:

01.08.2012 - 31.07.2017

Projektbeschreibung des Gastgebers

Für das Leben auf der Erde spielen Bakterien eine entscheidende Rolle. Sie unterstützen uns bei unserer Verdauung, helfen Müll abzubauen und sie haben mit die Atmosphäre unseres Planeten geschaffen. Andere wiederum sind tödlich und für eine Vielzahl von Krankheiten verantwortlich. Bakterien, die oft in einer Art Wohngemeinschaft vieler verschiedener Arten zusammenleben, bevölkern so unterschiedliche Welten wie Tiefseegräben und den menschlichen Verdauungstrakt. Neueste Sequenzierungstechniken und Fortschritte in Forschungsbereichen wie der Metagenomik, die die Gesamtheit einer Bakteriengemeinschaft Genomanalysen unterzieht, haben dazu geführt, dass jetzt umfassende Sequenzinformationen über die bakteriellen Gene zur Verfügung stehen. Dieses Wissen kann uns helfen, die Rolle der Bakterien für Gesundheit und Umwelt besser zu verstehen. Und dennoch bleiben wichtige Fragen offen. Über die Funktion von fast einem Drittel aller bekannten Gene weiß man wenig, und das trifft selbst auf die am intensivsten untersuchten Bakterienarten zu. Noch weniger gut untersucht ist, wie sich Gene und Proteine zu organisierten Einheiten, den Modulen, zusammenfinden und wie diese Module miteinander verschaltet sind.
Dr. Typas arbeitet mit systembiologischen Methoden und untersucht zugleich die molekularen Mechanismen der Bakterien. Seine Studien könnten einen wesentlichen Beitrag zum Verständnis der Genfunktion leisten, und wie Gene auf äußere Bedingungen reagieren, was den Bakterien ermöglicht, sich den verschiedensten Lebensbedingungen anzupassen. Im Mittelpunkt von Dr. Typas Forschung steht die Zellhülle, die jedes Bakterium umgibt. Diese Hülle schützt das Bakterium, entscheidet darüber, was in die Zelle gelangen kann und was nicht, und ist zugleich das Sinnesorgan, mit dem Bakterien ihre Umwelt wahrnehmen. Ist die genaue Architektur dieser Hülle erst einmal entschlüsselt, lassen sich eine Vielzahl von Mechanismen aufklären, wie beispielsweise Antibiotikaresistenzen, Virulenz, und wie sich Biofilme aus stark resistenten Bakteriengemeinschaften bilden und an Oberflächen anhaften können. Seine Studien könnten darüber hinaus helfen, neue Angriffspunkte für Medikamente zu identifizieren.

Heimatinstitut

Genome Biology
Europäisches Laboratorium für Molekularbiologie (EMBL)
Meyerhofstrasse 1
69117 Heidelberg

Professor Dr. Peter K. Vogt

Fachgebiet:

Virologie

In Deutschland:

16.02.1984 - 15.08.1984

Heimatinstitut

Department of Molecular & Experimental Medicine
Scripps Research Institute
North Torrey Pines Road 10550
92037 La Jolla

Professor Dr. John E. Volanakis

Fachgebiet:

Immunologie

In Deutschland:

01.07.1996 - 30.09.1996

Heimatinstitut

Department of Medicine
University of Alabama at Birmingham
1530 3rd Avenue South
35294 Birmingham

Professor Dr. Samuel Wagner

Fachgebiet:

Stoffwechselphysiologie, Biochemie und Genetik der Mikroorganismen

In Deutschland:

01.06.2017 - 31.12.2017

Projektbeschreibung des Gastgebers

Heimatinstitut

Institut für Medizinische Mikrobiologie und Hygiene
Eberhard Karls Universität Tübingen
Elfriede-Aulhorn-Straße 6
72076 Tübingen

Professor Dr. Richard Wenzel

Fachgebiet:

Medizinische Mikrobiologie und Mykologie und Hygiene, Molekulare Infektionsbiologie

In Deutschland:

01.10.1996 - 31.01.1997

Heimatinstitut

Department of Internal Medicine
Virginia Commonwealth University
1001 East Broad Street, Suite 405, PO Box 980663
23298-0663 Richmond

Professor Dr. Eckard A.F. Wimmer

Fachgebiet:

Virologie

In Deutschland:

01.11.1997 - 31.03.1998

Heimatinstitut

Department of Molecular Genetics and Microbiology
Stony Brook University
Life Sciences Bldg., Room 280
11794-5222 Stony Brook

Professorin Dr. Christiane Wobus

Fachgebiet:

Virologie

In Deutschland:

01.07.2014 - 30.06.2015

Projektbeschreibung des Gastgebers

Heimatinstitut

Medical School, Department of Microbiology and Immunology
University of Michigan
1150 West Medical Center Drive, 5641 Medical Science II
48109 Ann Arbor

Professorin Dr. Hua E. Yu

Fachgebiet:

Immunologie

In Deutschland:

01.06.2016 - 30.06.2016

Projektbeschreibung des Gastgebers

Heimatinstitut

Beckman Research Institute, Department of Cancer Biology
City of Hope National Medical Center
1500 East Duarte Road
91010 Duarte

Professor Dr. Diego de Mendoza

Fachgebiet:

Stoffwechselphysiologie, Biochemie und Genetik der Mikroorganismen

In Deutschland:

01.10.2011 - 30.09.2012

Projektbeschreibung des Gastgebers

Heimatinstitut

Department of Microbiology
Universidad Nacional de Rosario
Suipacha 531
S2002LRK Rosario