Field of Research:
Plant Genetics
In Germany:
01.09.2001 -
31.08.2005
Host's project description
Dr. Jane Parkers research activities are aimed at unravelling disease
resistance signalling pathways in the model plant, Arabidopsis. Some of these pathways are triggered by specific recognition between plant Resistance (R) gene and pathogen avirulence (avr) gene-encoded products. Other pathways exert low level "basal" resistance against virulent pathogens. Her group identified in mutational screens genes that are essential for R gene-triggered resistance. Two of these genes, EDS1 and PAD4 , are recruited by one structural class of intracellular, nucleotide-binding/leucine-rich repeat (NB-LRR) R proteins. EDS1 and PAD4 are also necessary for expression of basal resistance. Engagement of the other two genes, RAR1 and SGT1, is not determined by a particular NB-LRR protein type. Also, their activities appear to be restricted to R gene-conditioned responses.
In her future work, Jane Parker is going to use a combination of genetic, molecular and biochemical approaches to understand how the regulatory proteins EDS1, PAD4, RAR1, and SGT1 perform their respective roles in plant defence and discover which cellular processes they alter.
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Home Institute
Plant-Microbe Interactions
Max-Planck-Institut für Pflanzenzüchtungsforschung
Carl-von-Linne Weg 10
50829
Köln
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